| Date | Location | Result | |
| 03/08/22 | Las Vegas, NV | UTRGV 71, Seattle U 61 | Box score |
| 03/05/22 | Chicago, IL | Seattle U 57, Chicago St. 54 | Box score |
| 02/26/22 | Seattle, WA | Seattle U 69, Dixie St. 61 | Box score |
| 02/24/22 | Seattle, WA | Utah Valley 67, Seattle U 61 | Box score |
| 02/19/22 | Riverside, CA | California Baptist 83, Seattle U 73 | Box score |
| 02/16/22 | Seattle, WA | Seattle U 71, UTRGV 68 (OT) | Box score |
| 02/12/22 | Beaumont, TX | Seattle U 65, Lamar University 56 | Box score |
| 02/10/22 | Edinburg, TX | UTRGV 68, Seattle U 60 | Box score |
| 02/08/22 | Las Cruces, NM | New Mexico St. 59, Seattle U 54 | Box score |
| 02/05/22 | Seattle, WA | Seattle U 81, New Mexico St. 73 (OT) | Box score |
| 02/03/22 | Seattle, WA | Grand Canyon 64, Seattle U 59 | Box score |
| 01/20/22 | Seattle, WA | Seattle U 75, Abilene Christian 61 | Box score |
| 01/27/22 | Nacogdoches, TX | SFA 76, Seattle U 57 | Box score |
| 01/29/22 | Huntsville, TX | Sam Houston 73, Seattle U 54 | Box score |
| 01/22/22 | Seattle, WA | Tarleton St. 57, Seattle U 56 (OT) | Box score |
| 01/24/22 | Orem, UT | Utah Valley 65, Seattle U 51 | Box score |
| 01/15/22 | St. George, UT | Dixie St. 75, Seattle U 69 | Box score |
| 01/10/22 | Seattle, WA | Chicago St. 64, Seattle U 57 | Box score |
| 01/17/22 | Seattle, WA | California Baptist 76, Seattle U 66 | Box score |
| 12/20/21 | Seattle, WA | Seattle U 61, Western Ore. 38 | Box score |
| 12/18/21 | Bozeman, MT | Montana St. 76, Seattle U 49 | Box score |
| 12/16/21 | Missoula, MT | Montana 83, Seattle U 57 | Box score |
| 12/10/21 | Seattle, WA | Washington 77, Seattle U 59 | Box score |
| 12/02/21 | Boise, ID | Seattle U 63, Boise St. 61 | Box score |
| 11/09/21 | Seattle, WA | Seattle U 89, Northwest (WA) 32 | Box score |
| 11/26/21 | Las Vegas, NV | UTEP 62, Seattle U 57 | Box score |
| 11/25/21 | Las Vegas, NV | Seattle U 70, SMU 66 | Box score |
| 11/20/21 | Sacramento, CA | Seattle U 71, Sacramento St. 67 | Box score |
| 11/18/21 | Long Beach, CA | Long Beach St. 86, Seattle U 63 | Box score |
| 11/13/21 | Seattle, WA | UC San Diego 60, Seattle U 44 | Box score |